Commercial – APIs

Active Pharmaceutical Ingredient - APIs

Product Name Pharmacopeia Therapeutic Category CEP EDMF KDMF CHINA IDL TDMF TURKEY/ GCC RUSSIA COFERIS ANVISA
Acotiamide Hydrochloride Hydrate IH Gastrointestinal Agent     UA   UA   UA UA UA
Apixaban IH Anti-Coagulant Nov,22 Nov,22 Nov,22 Nov,22 Nov,22 Nov,22 Nov,22 Nov,22 Nov,22
Azelnidipine  IH Anti-Hypertensive                  
Bempedoic Acid IH Lipid Lowering Agent                  
Benfotiamine IH Vitamin B1   A A A A   A A A
Benidipine Hydrochloride JP Anti-Hypertensive     A UA   UA A A A
Bilastine IH Anti-Histamine     A A UA A A A A
Brivaracetam IH Anti-Convulsant                  
Citicoline Sodium IP/IH/USP Central Stimulant                  
Dapagliflozin Propanediol Monohydrate IH Anti-Diabetic                  
Delafloxacin Meglumine IH Anti-Bacterial                  
Fimasartan Trihydrate Potassium IH Anti-Hypertensive     AP A A A A A A
Gliclazide IP/BP/EP Anti-Diabetic                  
Levosulpiride IH Anti-Psychotic     OCT'22 OCT'22 OCT'22 OCT'22 OCT'22 OCT'22 OCT'22
Luliconazole IH Anti-Fungal                  
Mirabegron  IH Urologicals                  
Obeticholic Acid IH Gastrointestinal Agent                  
Oxaceprol IH Anti-Inflammatory                  
Prucalopride Succinate IH Prokinetic Agent     A A UA UA A A A
Rifaximin IH/EP Anti-Bacterial                  
Rivaroxaban IH/EP Anti-Coagulant                  
Sitagliptin Anti-Diabetic                  
Teneligliptin Hydrobromide Hydrate IH/IP Anti-Diabetic             UA    
Ticagrelor IH Anti-Coagulant                  
Ursodeoxycholic Acid IP/BP/USP Cholelithiasis Agent                  
Vildagliptin IH Anti-Diabetic              
Imeglimin IH Anti-Diabetic    
Molnupiravir IH Anti-Viral

Under-Development APIs

Commercial KSMs, Intermediates & Reagents

 

Product Name

CAS No.

Structure

End Use

Ethyl-2-Amino 1,3-Thiazole 4-Carboxylate

5398-36-7

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ACOTIAMIDE HCL HYDRATE

2,4,5-Trimethoxy Benzoic Acid

490-64-2

ACOTIAMIDE HCL HYDRATE

Ethyl 2-(2,4,5-trimethoxybenzamido)-1,3-thiazole-4-carboxylate

185105-98-0

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ACOTIAMIDE HCL HYDRATE

5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone(KSM)

545445-44-1

APIXABAN

3-AMINO-3-IMINOPROPANOIC ACID 1-(DIPHENYLMETHYL)-3-AZETIDINYL ESTER ACETATE

170749-59-4

AZELNIDIPINE

ISOPROPYL 2-(3-NITROBENZYLIDENE)ACETOACETATE

39562-25-9

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AZELNIDIPINE

1-benzhydryl-3-azetidinyl amidinoacetate

116574-09-5

AZELNIDIPINE

2-(2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole

202189-77-3

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BILASTINE

(R)-4-PROPYLDIHYDROFURAN-2-(3H)

63095-51-2

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BRIVARACETAM

Choline phosphate chloride calcium

(Calcium phosphorylcholine chloride)

4826-71-5

CITICOLINE SODIUM

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl) methyl]phenyl]-, 2,3,4,6-tetraacetate, (1S)

461432-25-7

DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE

Ethyl 1-(6-amino-3,5-difluoro-2-pyridinyl)-6-fluoro-1,4-dihydro-7-[3-(2-methyl-1-oxopropoxy)-1-azetidinyl]-4-oxo-3-quinolinecarboxylate

442526-91-2

DELAFLOXACIN MEGLUMINE

ABT- 492 Meglumine

352458-37-8

DELAFLOXACIN MEGLUMINE

2,3,4,6-tetrakis-O-(trimethylsilyl)-D-glucopyranone

32384-65-9

EMPAGLIFLOZIN / DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE

2-Butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]pyrimidin-4(3H)-one

247257-48-3

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FIMASARTAN TRIHYDRATE POTASSIUM

2-(2-butyl-4-hydroxy-6-Methylpyrimidin-5-yl)-N,N-dimethylacetamide (Fima-Pyrimidinamide)

1315478-13-7

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FIMASARTAN TRIHYDRATE POTASSIUM

(S)-N-ethyl-2-aminomethyl pyrrolidine

22795-99-9

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LEVOSULPIRIDE

Pyrrolidine,1-ethyl-2-(nitromethyl)

26171-04-0

26171-04-0 1-ethyl-2-(nitromethylene)pyrrolidine

LEVOSULPIRIDE

(1R), 2-chloro-1-(2,4-dichlorophenyl)ethan-1-ol

114446-57-0

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LULICONAZOLE

1-(Cyanomethyl) Imidazole Hydrochloride

220476-15-3

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LULICONAZOLE

Imidazole 1-acetonitrile Mesylate

not assigned

LULICONAZOLE

2-Aminothiazol-4-yl) Acetic acid

29676-71-9

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MIRABEGRON

(R)-2-hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide

521284-19-5

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MIRABEGRON

(R)-2-[[2'-(4-nitropheny])-ethyl]amino]-1-phenylethanol monohydrochloride

521284-21-9

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MIRABEGRON

(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride (1:1)

521284-22-0

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MIRABEGRON

Uridine, 4-oxime

3258-02-4

Chemical Structure| 3258-02-4

MOLNUPIRAVIR

3alpha-hydroxy-6-ethylidene-7keto-5beta cholanoic acid

1885104-64-2

OBETICHOLIC ACID

1-(3-methoxypropyl)piperidin-4-amine

179474-79-4

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PRUCALOPRIDE SUCCINATE

4-amino-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylic acid

123654-26-2

4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid.png

PRUCALOPRIDE SUCCINATE

2-{(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl) aniline] propyl}-1-H-isoindole-1,3(2H)-dione

446292-07-5

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RIVAROXABAN

1-H isoindole-1,3-(2H)-dione,  2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-

446292-08-6

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RIVAROXABAN

(S)-4-[4-[5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholin-3-one hydrochloride

898543-06-1

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RIVAROXABAN

(2S)-4-oxo-2-(3-thiazolidinyl carbonyl)-1-pyrrolidine carboxylic acid Tert-butyl ester

401564-36-1

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TENELIGLIPTIN HYDROBROMIDE HYDRATE

1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine

401566-79-8

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TENELIGLIPTIN HYDROBROMIDE HYDRATE

(2S)-1-(Chloroacetyl)-2- pyrrolidine-carbonitrile (Vila-Nitrile)

207557-35-5

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VILDAGLIPTIN

Lawesson’s reagent

19172-47-5

           FIMASARTAN

 

Under-development KSMs, Intermediates & Reagents

Product Name

CAS No.

Structure

End Use

Status

N,N-Diisopropyl Ethylene diamine

7087-68-5

download

ACOTIAMIDE HCL HYDRATE

1,4-DIHYDRO-26-DIMETHYL-4-(3-NITROPHENYL)-35-PYRIDINEDICARBOXYLIC ACID 3-METHYL ESTER

74936-72-4

imgsrv

BENIDIPINE HYDROCHLORIDE

N-BENZYL-3-HYDROXYPIPERIDINE

14813-01-5

N-Benzyl-3-hydroxypiperidine 97%

BENIDIPINE HYDROCHLORIDE

2-(4-(1-(4,4-dimethyl-∆2-oxazoline-2-yl)-1-methylethyl)phenyl)ethyl p-toluene sulphonate.

202189-76-2

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate.png

BILASTINE

5-bromo-2-chloro-4'-ethoxydiphenylmethane

461432-23-5

DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE

4-(5-bromo-2-chloro-benzyl)-phenol

864070-18-8

4-(5-Bromo-2-chlorobenzyl)phenol.png

EMPAGLIFLOZIN

(R)-3-(4-methylphenylsulfonyloxy)-tetrahydrofuran

219823-47-9

https://wscpimg.sial.com/5/8/128464658_w290.png

EMPAGLIFLOZIN

N-Amino-3-Azabicyclo(3.3.0)Octane hydrochloride

58108-05-7

https://media.scbt.com/product/3-amino-3-azabicyclo3-3-0octane-hydrochloride-58108-05-7-_12_08_b_120807.jpg

GLICLAZIDE

Trans-(4-methylcyclohexyl) amine HCL  (CHH)

33483-65-7

GLIMEPIRIDE

3-Ethyl-4-methyl-l, 5-dihydro-1H-pyrrol-2-one

766-36-9

3-Ethyl-4-methyl-3-pyrrolin-2-one: sc-254468...

GLIMEPIRIDE

2-phenylethyl isocyanate

1943-82-4

Phenethyl isocyanate 98%

GLIMEPIRIDE

8-Bromo-3-methyl-xanthine

93703-24-3

LINAGLIPTIN

1-Bromo-but-2-yne

3355-28-0

LINAGLIPTIN

2-(chloromethyl)-4-methylquinazoline

109113-72-6

LINAGLIPTIN

(R)-3-tert-Butoxycarbonylaminopiperidine

309956-78-3

LINAGLIPTIN

2,4,5-Trifluorobenzeneacetic acid

209995-38-0

SITAGLIPTIN

3-(trifluoromethyl)-5,6,7,8-tetrahydro [1,2,4]triazolo[4,3-a]pyrazine HCl

762240-92-6

SITAGLIPTIN

2-{[(3aR,4S,6R,6aS)-6-{[5-Amino-6-chloro-2-(propylsulfanyl)-4-pyr imidinyl]amino}-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]diox ol-4-yl]oxy}ethanol

376608-74-1

TICAGRELOR

4,6-dichloro-2-(propylthio)-pyrimidin-5-amine

145783-15-9

TICAGRELOR

2,4-dimethylbenzenethiol

13616-82-5

VORTIOXETINE HBr

2-bromonitrobenzene

577-19-5

VORTIOXETINE HBr

(1R,2S)-2-(3,4-difluorophenyl)-cyclopropan aminium-(2R)-hydroxy (phenyl)ethanoate

376608-71-8

TICAGRELOR

n-Butyl Lithium

109-72-8

n-Butyllithium solution 2.5 M in hexanes

DAPAGLIFLOZIN

Services

1. CRAMS

Kimia Biosciences offers Contract Research and Manufacturing and Development Services across the entire value chain of a new chemical entity which covers from Pre-Clinical to Commercial Phase. We have a strong and dynamic team of scientists functioning from research centers, which are supported by a highly compliant manufacturing footprint with robust multi-product facilities.

As an imminent CRO-CDMO player, we envisaged to work with India and global innovator pharma companies to accelerate the discovery, development, and commercialisation of their NCE small molecule programmes.

Our Expertise from early Discovery to Commercial supply;

Robust Supply Chain

1. Comfort to customers with a backward integrated setup that ensures supply assurance of the key intermediates.

2. Scalable infrastructure to counter supply chain oversights going forward

3. Work with clients in flexible, adaptable and customized partnership model for small molecules.

Quality Committed

1. Committed to deliver services with sustain focus on quality, affordable innovation and productivity

One Stop Solution for your Chemical Needs

1. Offering services from mg to metric ton scale

2. We cover the entire life cycle of a new chemical entity at all scales, from pre-clinical and clinical phases to validation and commercial supply, while fully complying with cGMP regulations and standards within WHO GMP, FDA approved facilities.

Environment, Health and Safety

1. We comply with all applicable EHS Legal and other requirements

2. We optimize our resources in a way to prevent and reduce pollution, energy consumption and to increase water conservation.

2. Kimia upcoming CDMO-CRO services:

Chemistry, manufacturing and controls

Kimia Biosciences has a strong team of scientists and process engineers. We are up to any challenge involving complex chemical synthesis, from route scouting, process development, and scale-up to commercial scale.
As a contract manufacturing organisation (CMO), we make high-quality APIs and intermediates that serve the highly regulated markets of the USA, Europe, and Japan etc. Our world-class manufacturing facilities are equipped with flexible and versatile infrastructure, and we are continuously striving to make it better. 

 Services

1. Route Scouting

2. Establishing innovative Route of Synthesis (ROS) from an idea to a sustainable process

3.Process familiarisation, optimisation & development

4. Phase-appropriate process development to ensure successful scale-up and timely product delivery for your clinical trials

5. Analytical method development & validation

6. Phase-appropriate analytical methods using complementing techniques

7. Process safety evaluation

8. Rigorous, data-driven Process Safety evaluation

9. Stability studies

10. Comprehensive range of stability services across time zones

11. Early phase scale-up

Discovery

Kimia Biosciences is a trusted small molecule CRO partner envisaged to help innovator Pharma companies accelerate their drug discovery journey from HIT to IND using creative chemistry supported by high quality , DMPK, toxicology and cGMP scale-up services.

We are known to be responsive, flexible and cost-effective in delivering solutions tailored to suit the program requirements. Our strong and growing scientific team provides a fully-integrated service bringing the collective expertise of various teams together to develop a lead candidate.

3. Other Services

1. Integrated Drug Discovery Services

2. Discovery services spanning the entire journey from target ID and validation to IND

3. Synthetic & medicinal chemistry

4. Specializing in the synthesis of complex chemical entities to advance your drug discovery programs

KIMIA BIOSCIENCE LIMITED
974, Aggarwal Millennium Tower II,
Netaji Subhash Place, Pitampura,
New Delhi-110 034
+91-11-4706 3600
info@kimiabiosciences.com

Kimia Biosciences Ltd™ is engaged in manufacturing of bulk drugs addressing to various high potential therapeutic segments and has envisaged high growth plans through infrastructure creation and CMS.